News Scan
Changes in Antidepressant Metabolism and Dosing Across Pregnancy and Early Postpartum
Our cases illustrate that dose requirements frequently increase during the second half of pregnancy to offset increased drug turnover and maintain optimal pharmacotherapy. These findings replicate and extend earlier published data with other antidepressants.
Maternal Depressive Symptoms in Pediatric Major Depressive Disorder: Relationship to Acute Treatment Outcome.
This study indicates a positive relationship between the depression severity of mothers and their children. These findings highlight potential areas of intervention in the acute treatment of childhood depression.
Depressive Symptoms and the Risk of Atherosclerotic Progression Among Patients With Coronary Artery Bypass Grafts
These findings suggest that depressive symptoms are associated with a higher risk of atherosclerotic progression among patients with saphenous vein grafts and that aggressive lipid lowering can minimize this increased risk. Whether depressive symptoms increase progression in other types of coronary atherosclerosis and whether aggressive lipid lowering attenuates such progression will require additional study.
http://circ.ahajournals.org/cgi/content/abstract/CIRCULATIONAHA.107.741058v1
Deep Brain Stimulation May Offer Hope For Select Patients With Treatment Resistant Major Depression
Researchers from the Cleveland Clinic, Brown University, and Massachusetts General Hospital will present results of a long-term outcome study that builds on previous promising research, which has shown that deep brain stimulation (DBS) is a potentially effective treatment option for people with treatment resistant major depression.
http://www.medicalnewstoday.com/articles/105604.php
Late-Pregnancy Depression Predicts Postnatal Woes
Helping women who suffer from depression during pregnancy could reduce their risk of remaining depressed after giving birth and, in turn, reduce the level of stress they experience in early parenthood, Australian researchers report.
http://www.nlm.nih.gov/medlineplus/news/fullstory_63978.html
